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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
34.24
Human Site:
Y877
Identified Species:
47.08
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
Y877
L
E
N
L
K
D
E
Y
V
R
T
L
E
E
T
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
Y877
L
E
N
L
K
D
E
Y
V
R
T
L
E
E
T
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
Y876
L
E
N
L
K
D
E
Y
V
R
T
L
E
E
T
Dog
Lupus familis
XP_533766
1089
122761
Y874
L
E
N
L
K
D
E
Y
V
R
T
L
E
E
T
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
Y875
L
E
N
I
K
D
E
Y
V
R
T
L
E
E
S
Rat
Rattus norvegicus
NP_446123
1093
121882
Y877
L
E
N
L
K
D
E
Y
V
R
T
L
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
Y884
L
E
N
L
K
D
E
Y
F
N
A
L
E
E
T
Chicken
Gallus gallus
O42184
1433
161009
N1034
D
I
K
G
F
K
Q
N
L
L
D
A
E
E
A
Frog
Xenopus laevis
Q5PQ23
649
75475
W447
A
L
S
S
A
E
T
W
R
S
R
Y
N
K
L
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
Y912
L
E
N
L
K
G
E
Y
A
R
V
S
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
T730
E
E
Q
R
K
Q
P
T
L
L
T
V
K
A
V
Honey Bee
Apis mellifera
XP_394037
1326
150590
A995
L
K
E
A
T
T
N
A
G
E
S
C
Q
L
L
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
L1503
A
K
N
A
Q
E
E
L
A
E
V
V
E
G
L
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
Y957
M
E
N
Q
L
Q
N
Y
L
R
S
V
E
E
A
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
R773
L
L
Q
Q
E
I
E
R
E
K
A
A
R
L
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
N754
L
Q
E
V
L
L
H
N
E
L
I
Q
K
D
L
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
M505
T
L
P
Q
E
N
S
M
L
S
L
S
M
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
80
13.3
0
60
N.A.
20
6.6
20
40
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
80
26.6
26.6
73.3
N.A.
40
26.6
46.6
66.6
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
12
6
0
0
6
12
0
12
12
0
6
18
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% C
% Asp:
6
0
0
0
0
42
0
0
0
0
6
0
0
12
0
% D
% Glu:
6
59
12
0
12
12
59
0
12
12
0
0
65
53
6
% E
% Phe:
0
0
0
0
6
0
0
0
6
0
0
0
0
0
0
% F
% Gly:
0
0
0
6
0
6
0
0
6
0
0
0
0
6
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
6
0
6
0
0
0
0
6
0
0
0
0
% I
% Lys:
0
12
6
0
53
6
0
0
0
6
0
0
12
6
6
% K
% Leu:
65
18
0
42
12
6
0
6
24
18
6
42
0
12
24
% L
% Met:
6
0
0
0
0
0
0
6
0
0
0
0
6
0
0
% M
% Asn:
0
0
59
0
0
6
12
12
0
6
0
0
6
0
0
% N
% Pro:
0
0
6
0
0
0
6
0
0
0
0
0
0
0
0
% P
% Gln:
0
6
12
18
6
12
6
0
0
0
0
6
6
0
0
% Q
% Arg:
0
0
0
6
0
0
0
6
6
48
6
0
6
0
0
% R
% Ser:
0
0
6
6
0
0
6
0
0
12
12
12
0
6
12
% S
% Thr:
6
0
0
0
6
6
6
6
0
0
42
0
0
0
30
% T
% Val:
0
0
0
6
0
0
0
0
36
0
12
18
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
53
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _